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Leader of the Coordination Center:
Prof. Dr. med. Günther Deuschl
phone: ++49 431 5978500
fax: ++49 431 5978502
email: g.deuschl@neurologie.uni-kiel.de
Leader of the study project TP3: Deep brain stimulation
Prof. Dr. med. Günther Deuschl
phone: ++49 431 5978500
email: g.deuschl@neurologie.uni-kiel.de
Role of the institution in the Competence Network on Parkinson’s disease
The Department of Neurology at the University of Kiel is one of five coordination centres within the Competence Network on Parkinson’s disease. It is responsible for running the horizontal network structure in the northern area. There are plans to link with other local medical networks. Kiel is coordinating Project 3, a multicentre study looking at the effct of deep brain stimulation on life quality in patients suffering from Parkinson's disease. Motor, psychogical and psychiatric aspects will be evaluated. Intra-operative recording of cell potentials will be undertaken in order to investigate the pattern of neuronal discharge in the basal ganglia area. The mechanisms of deep brain stimulation will be examined in a cat model in co-operation with the Department of Physiology.
Description of the institution
Clinic:
The Department of Neurology at the University of Kiel covers the whole spectrum of neurology. The clinical and research activity focuses on movement disorders, pain, cerebrovascular diseases and intensive care neurology. Movement disorders are treated in both in- and outpa-tient settings, including the provision of Botulinum toxin therapy. The interdisciplinary team is specialized in the therapy of advanced Parkinson's disease, and undertakes preoperative consultation prior to the implantation of deep brain stimulators (in cooperation with the De-partment of Neurosurgery at the University of Kiel and the Department of Functional Sterotactic Neurosurgery at the University of Hamburg) and pEastoperative management of these patients. Further specialist interests are the diagnosis and treatment of rare hyperkinetic movement disorders, particulary tremor.
Research:
The research work focuses on the effects and mechanisms of deep brain stimulation in Parkinson's disease, the pathophysiology of tremor, differential diagnoses and pathophysiology of gait disorders, rehabilitation of grip movements and locomotion after brain injury. The Motor Research Laboratory provides the necessary research facilities. Animal model research covis beign undertaken in the pathophysiology of tremor (olivarhypertrophy in rats), the role of microglia in apoptosis in a mice parkinson model (in cooperation with the Department of Anat-omy at Kiel) and the pathophysiology of Parkinson's disease in a cat model (in cooperation with the Department of Physiology at Kiel).
Further information
in the internet
www.uni-kiel.de/neurologie
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